Welcome visitor you can login or create an account.

Shopping Cart

0 item(s) - $0.00
Your shopping cart is empty!
Bovine Brain Microvascular Endothelial Cells (BBMVEC)

Bovine Brain Microvascular Endothelial Cells (BBMVEC)

Catalog Number: 10BO-005
Availability: Out Of Stock
Price: $559.00

Available Options

* Package Size (Required):

Qty:     - OR -   Add to Wish List
Add to Compare

Product Description

Brain microvascular endothelial cells (BMEC), the major component of the blood-brain barrier, limit the passage of substances, both soluble and cellular, from the blood into the brain. BMEC utilize unique features to distinguish themselves from peripheral endothelial cells, such as 1) intercellular tight junctions that display high electrical resistance and slow paracellular transport, 2) the absence of fenestrae and a reduced level of pinocytic activity, and 3) the expression of specialized pumps that can transport compounds out of the brain via the blood-brain barrier [1-3]. Similar to peripheral endothelial cells, BMEC express, or can be induced to express, cell adhesion molecules on their surface that regulate the extravasation of leukocytes into the brain. Cultured bovine BMEC have been used for studying the molecular and cellular properties of blood-brain barrier because of their unique functions [4]. Understanding the molecular mechanisms of blood-brain barrier regulation may help to optimize drug delivery to the CNS and elucidate new therapies for CNS diseases. 

iXCells Biotechnologies provides high quality Bovine Brain Microvasular Endothelial Cells (BBMVEC), which are isolated from bovine brain and cryopreserved at P1, with >0.5 million cells in each vial. BBMVEC express vWF/Factor VIII and are negative for mycoplasma, bacteria, yeast, and fungi. They can further expand for 5 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies. 

Product Details


  Bovine brain

  Package Size

  0.5 million cells/vial  

  Passage Number





  Liquid nitrogen

  Growth Properties



  Endothelial Cell Growth Medium (Cat# MD-0010)

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we make no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

Related Products (1)
Name Description Catalog number
Endothelial Cell Growth Medium MD-0010