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Mouse Salivary Gland Fibroblasts (MSGF)

Mouse Salivary Gland Fibroblasts (MSGF)

Catalog Number: 10MU-028
Availability: Out Of Stock
Price: $349.00

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Product Description

The salivary gland produces enzyme-containing saliva to lubricate the oral cavity and assist with digestion. It consists of three pairs of major salivary glands and many minor ones in the oral cavity [1]. Histology studies show that the salivary gland is a compound tubuloalveolar gland, surrounded by connective tissue to further divide the gland into lobes and lobules. The secretory end pieces consist of a spherical mass of cells called acinus. Mouse salivary gland fibroblasts (MSGF) are embryonic mesoderm derived mesenchymal cells and they are responsible for synthesis of extracellular matrix such as type I and/or type III collagen [2]. MSGF are very versatile and provide a useful tool for studying collagenous fibroma and oral neoplasms [3].

iXCells Biotechnologies provides high quality Mouse Salivary Gland Fibroblasts (MSGF), which are isolated from postnatal day 2 C57BL/6 mouse salivary gland and cryopreserved at P1, with >0.5 million cells in each vial. MSGF express fibronectin and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand for 5 population doublings in Fibroblast Growth Medium (Cat# MD-0011) under the condition suggested by iXCells Biotechnologies.

Product Details

  Tissue

  Postnatal day 2 mouse salivary gland (strain C57BL/6) 

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Fibroblast Growth Medium (Cat# MD-0011)

References

[1] Baker OJ. (2010) “Tight junctions in salivary epithelium.” J Biomed Biotechnol. 2010: 278948. 
[2] Gabbiani G, Rungger-Brandle E. (1981) “The fibroblast.” In Glynn LE, Handbook of Inflammation, Vol. 3: Tissue Repair and Regeneration (pp 1-50). Amsterdam: Elsevier.
[3] Ide F, Shimoyama T, Horie N, Tanaka H. (1999) “Collagenous fibroma (desmoplastic fibroblastoma) presenting as a parotid mass.” J Oral Pathol Med. 28: 465-8.

[1] Baker OJ. (2010) “Tight junctions in salivary epithelium.” J Biomed Biotechnol. 2010: 278948. 
[2] Gabbiani G, Rungger-Brandle E. (1981) “The fibroblast.” In Glynn LE, Handbook of Inflammation, Vol. 3: Tissue Repair and Regeneration (pp 1-50). Amsterdam: Elsevier.
[3] Ide F, Shimoyama T, Horie N, Tanaka H. (1999) “Collagenous fibroma (desmoplastic fibroblastoma) presenting as a parotid mass.” J Oral Pathol Med. 28: 465-8.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we make no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Fibroblast Growth Medium MD-0011