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Porcine Corneal Epithelial Cells (PCEpC)

Porcine Corneal Epithelial Cells (PCEpC)

Catalog Number: 10PO-003
Availability: Out Of Stock
Price: $499.00

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Product Description

The cornea is a unique tissue for two reasons: the transparency function and the synthesis of most of its proteins due to the cornea being an avascular tissue. The cornea consists of three distinct cell layers: the outer epithelium, the inner endothelium and the central stroma (the keratocytes). The corneal epithelium plays a role in the innate immune response by sensing the presence of pathogens and providing signals that activate the corneal defense system [1]. It also highly expresses aldehyde dehydrogenase to protect against UV- and 4-hydroxynonenal-induced cellular damage [2]. Corneal epithelial basal cell proliferation is controlled by a host of cytokines, e.g., epidermal growth factor, that activate their cognate receptors in the deeper layers of the epithelium [3]. Instead of testing products in the eyes of animals, cultured corneal epithelial cells could be used for toxicology tests in in vitro models and for studying the molecular mechanisms involved in regulating human corneal epithelial cell differentiation.

iXCells Biotechnologies provides high quality Porcine Corneal Epithelial Cells (PCEpC), which are isolated from porcine cornea and cryopreserved at P1, with >0.5 million cells in each vial. PCEpC express CK-18 and -19 and are characterized by their cobble stone morphology in serum-free culture. They are negative for mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in Corneal Epithelial Cell Growth Medium (Cat# MD-0064) under the condition suggested by iXCells Biotechnologies.                                                                                  .

Product Details

  Tissue

  Porcine cornea

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Corneal Epithelial Cell Growth Medium (Cat# MD-0064)

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we make no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Corneal Epithelial Cell Growth Medium MD-0064