Starting at: $579.00
| SKU | Package Size | Price | Quantity | Add to Cart |
|---|---|---|---|---|
| 10RA-032 | Cryopreserved, 2.0 million cells/vial | Starting at: $579.00 |
Product Description
Cortical neurons make up a large portion of the brain and consist of both glutamateric and GABA-ergic neurons [1]. They play an important role in higher level thought processes and are necessary to organize input from subcortical structures. Like all neurons, these cells transport Na+ that work to propagate action potentials from one cell to the next, which is the basis of a working neural pathway. These cells can be used to study a variety of cortical related abnormalities including Huntington’s Disease, Alzheimer’s Disease, psychiatric disorders, and learning disorders [2, 3].
iXCells Biotechnologies provides high quality Rat Cortical Neurons (RCN), which are isolated from the brains of E16 embryonic rats. These cells are cryopreserved at P0, with ≥ 2 million cells in each vial. They are negative for mycoplasma, bacteria, yeast, and fungi. RCNs can be plated using Rat Cortical Neuron Recovery Medium (Cat# MD-0107A) and maintained in Rat Cortical Neuron Maintenance Medium (Cat# MD-0107B) under the condition suggested by iXCells Biotechnologies.
Figure 1. Rat Cortical Neuron (Cat# 10RA-032) were recovered and cultured for 5 days. (A) Phase contrast image. (B) Immunofluorescence staining were performed using antibodies against the neuronal markers MAP2 (green) and NeuN (red).
Product Details
| Tissue | D16 embryo rat brain tissue |
| Package Size | 2.0 millioncells/vial |
| Passage Number | P0 |
| Shipped | Cryopreserved |
| Storage | Liquid nitrogen |
| Growth Properties | Adherent |
| Media | Rat Cortical Neuron Recovery Medium (Cat# MD-0107A) Rat Cortical Neuron Maintenance Medium (Cat# MD-0107B) |
Reference
[1] Johnson M, Walsh C. (2017) ” Cerebral Cortical Neuron Diversity and Development at Single-Cell Resolution ” Curr Opin Neurobiol. 42: 9-16.
[2] Lim L, Mi D, Llorca A, Marin O. (2018) ” Development and functional diversification of cortical interneurons.” Neuron. 100(2): 294-313.
[3] Molnár Z, Clowry G J, Šestan N, Alzu’bi A, Bakken T, Hevner R F, et al. (2019) ” New insights into the development of the human cerebral cortex.” J. Anat. 235: 432-451.
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