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Recombinant Human 4-1BB Receptor (TNFRSF9)

Catalog Number: IX101425
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Price: $856.80

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Alternative Names Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD_antigen=CD137, CD137, ILA
Recombinant Human 4-1BB (TNFRSF9)
Description 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a costimulatory signal to resting T cells leading to high level IL-2 production independently of CD28 signaling.
Gene Symbol TNFRSF9
Gene ID 3604
Accession No. Q07011
Source CHO cells
Appearance Lyophilized Powder
Molecular Weight 65.0 kDa
Endotoxin Level <1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Bioactivity The activity was tested by the ability of immobilized recombinant mouse 4-1BBL to bind human 4-1BB with a linear range of 10-500 ng/mL.
Formulation Recombinant Human CD137 is lyophilized from 0.2 μm filtered PBS solution, pH7.2.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage Recombinant Human CD137 can be stored in working aliquots at 2° - 8°C for one month, or at -20°C to -70°C for twelve months. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.