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Recombinant Human AKT2 (N-His tag)

Catalog Number: IX500006
Availability: In Stock
Price: $371.70

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Alternative Names PRKBB; PKBBETA; RAC-BETA
Description AKT2 or Protein Kinase B ß (PKBß) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility. The PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of AKT2 to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1).
Gene Symbol AKT2/PKB beta
Accession No. NM_001626
Source Insect cells
Appearance Liquid
Molecular Weight 58.0 kDa
Purity 70% - 90%
Bioactivity The specific activity of AKT2 was determined to be 44 nmol /min/mg as per activity assay protocol.
Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Storage Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.