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Human Adrenal Cortical Cells (HAdCC)

Human Adrenal Cortical Cells (HAdCC)

Catalog Number: 10HU-033
Availability: In Stock
Price: $619.00

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Product Description

The adrenal cortex makes up the perimeter of the adrenal gland and plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid and androgen hormones. The secreted steroids arise from the three zones that form the adrenal gland and these zones provide the framework for the adrenal cortex. The cells in the cortex stem from the mesoderm and form three concentric zones: the zona glomerulosa, zona fasciculate, and zona reticularis. Studies have shown that there is extensive interaction between the cortical and medulla regions of the adrenal gland, with cortical cells located within the adrenal medulla and chromaffin cells located within the adrenal cortex. The close contact of these two cell types implies intercellular exchange and allows for further studies of paracrine signaling between the two adrenal endocrine systems [1]. Adrenal cortical cells can be used for further research of hormonal regulation and steroidogenesis. 

HAdCC from iXCells are isolated from human adrenal cortical tissue. HAdCC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HAdCC are characterized by immunofluorescence with antibodies specific to GFAP. HAdCC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAdCC are guaranteed to further culture for 12 population doublings in Mesenchymal Stem Cell Medium (Cat# .MD-0037).

Product Details

  Tissue

  Human adrenal cortical tissue

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Mesenchymal Stem Cell Medium (Cat# .MD-0037)

References

[1] Arnold, J., 1866. Ein Beitrag zu der feiner Struktur und dem Chemismus der Nebennieren. Virchows Arch. Pathol. Anat. Physiol. Klin. Med. 35, 64: 107.
[2] Bornstein et al. (1994) Intimate contact of chromaffin and cortical cells within the human adrenal gland forms the cellular basis for important intraadrenal interactions. JCEM. 78(1): 225.

[1] Arnold, J., 1866. Ein Beitrag zu der feiner Struktur und dem Chemismus der Nebennieren. Virchows Arch. Pathol. Anat. Physiol. Klin. Med. 35, 64: 107.
[2] Bornstein et al. (1994) Intimate contact of chromaffin and cortical cells within the human adrenal gland forms the cellular basis for important intraadrenal interactions. JCEM. 78(1): 225.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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