/HBVP-Phase-300x300.jpg)
Human Brain Vascular Pericytes (HBVP)
Catalog Number: | 10HU-031 |
Availability: | In Stock |
Add to Compare
Product Description
Pericytes are contractile cells that wrap around the endothelial cells of capillary and venules throughout the body[1]. Pericytes are embedded in basement membrane, where they communicate with endothelial cells by means of direct physical contact and paracrine signaling[2]. In the brain, pericytes help sustain the blood-brain barriers, which regulate capillary blood flow, the clearance and phagocytosis of cellular debris and the permeability of the blood-brain barrier. Pericytes deficiency in the central nervous system can cause the blood-brain barrier breakdown, leading to neurodegenerative diseases.
Figure 1. Phase contrast image of Human Brain Vascular Pericytes.
Figure 2. Immunofluorescence staining of Human Brain Vascular Pericytes with Alpha-SMA antibody.
iXCells Biotechnologies provides high quality Human Brain Vascular Pericytes (HBVP), which are isolated from human brain and cryopreserved at P2, with >0.5 million cells in each vial. These HBVP are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand in Human Pericyte Growth Medium (Cat# MD-0030) under the condition suggested by iXCells Biotechnologies.
Product Details
Tissue |
Human brain tissue |
Package Size |
0.5 million cells/vial |
Passage Number |
P2 |
Shipped |
Cryopreserved |
Storage |
Liquid nitrogen |
Growth Properties |
Adherent |
Media |
References
[1] Birbrair etc and Osvaldo. Role fo pericytes in skeletal muscle regeneration and fat accumulation. Stem Cell and Development 2013, 22(16): 2298-2314.
[2] Bergers G and Song S. The role of pericytes in blood-vessel formation and maintenance. Neuro-Oncology 2005, 7(4): 452-464.
[1] Birbrair etc and Osvaldo. Role fo pericytes in skeletal muscle regeneration and fat accumulation. Stem Cell and Development 2013, 22(16): 2298-2314.
[2] Bergers G and Song S. The role of pericytes in blood-vessel formation and maintenance. Neuro-Oncology 2005, 7(4): 452-464.
This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.
This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.
© iXCells Biotechnologies 2015. All rights reserved.