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Human Endometrial Microvascular Endothelial Cells (HEMEC)

Human Endometrial Microvascular Endothelial Cells (HEMEC)

Catalog Number: 10HU-059
Availability: Out Of Stock
Price: $629.00

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Product Description

Angiogenesis is critical for many physiological processes including organ development, tissue repair, and the female reproductive tract [1,2]. Human endometrial microvascular endothelial cells (HEMEC) are located in the inner mucous membrane of the uterus known as the endometrium. HEMEC are involved in endometrial angiogenesis during the menstrual cycle with the rapid growth and shedding of the endometrium. Angiogenesis in the endometrium occurs through the non-sprouting mechanisms intussusception and vessel elongation [2,3]. Studies have indicated that elevated HEMEC proliferation in the endometrium can lead to disorders such as endometriosis and menorrhagia [3]. Cultured HEMEC are a useful model to elucidate the mechanisms of normal and pathological angiogenesis and develop treatments for female reproductive tract disorders. 

iXCells Biotechnologies provides high quality HEMEC, which are isolated from human uterus and cryopreserved at P1, with >0.5 million cells in each vial. HEMEC express vWF/Factor VIII, CD31 (PECAM), and Dil-Ac-LDL by uptake. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies. 

Product Details

  Tissue

  Human uterus

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Endothelial Cell Growth Medium (Cat# MD-0010)

References

[1] Scott PAE, Bicknell R. (1993). The isolation and culture of microvascular endothelium. J Cell Sci. 105: 269-73.
[2] Rogers P, Lederman F, Taylor N. (1998). Endometrial microvascular growth in normal and dysfunctional states. Hum Reprod Update. 4(5): 503-508.
[3] Gargett C, Rogers P. (2001). Human endometrial angiogenesis. Reproduction. 121: 181-186.

[1] Scott PAE, Bicknell R. (1993). The isolation and culture of microvascular endothelium. J Cell Sci. 105: 269-73.
[2] Rogers P, Lederman F, Taylor N. (1998). Endometrial microvascular growth in normal and dysfunctional states. Hum Reprod Update. 4(5): 503-508.
[3] Gargett C, Rogers P. (2001). Human endometrial angiogenesis. Reproduction. 121: 181-186.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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