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Human Mammary Epithelial Cells (HMEpC)

Human Mammary Epithelial Cells (HMEpC)

Catalog Number: 10HU-104
Availability: Out Of Stock
Price: $549.00

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Product Description

Human mammary epithelial cells (HMEpC) lie within the alveolar lumen of the breast lobules, which together with mammary ducts and adipose tissues, form a complex network in the mammary gland. HMEpC respond to various growth factors and hormonal cues and undergo changes in growth, invasion, and differentiation during pre- and postnatal stages, puberty, and pregnancy [1]. Aberrant levels of hormones and extracellular matrix composition, and other genetic factors have been shown to induce uncontrolled proliferation of HMEpC, resulting in breast cancer development [2, 3]. Understanding the cellular properties of HMEpC will help identify the disease mechanisms in breast cancer and the new targets for therapeutic development.

iXCells Biotechnologies provides high quality HMEpC, which are isolated from human breast and cryopreserved at P1, with >0.5 million cells in each vial. HMEpC express cytokeratine-14, -18, and -19. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in Epithelial Cell Growth Medium (Cat# MD-0041) under the condition suggested by iXCells Biotechnologies. 

Product Details

  Tissue

  Human breast

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Epithelial Cell Growth Medium (Cat# MD-0041)

References

[1]. Topper, Y.J., Freeman, C.S. (1980) Multiple hormone interactions in the developmental biology of the mammary gland. Physiol Rev 60:1049-106. 
[2]. Hennighausen, L., Robinson, G.W. (2001) Signaling pathways in mammary gland development. Dev Cell 1:467-475.

[1]. Topper, Y.J., Freeman, C.S. (1980) Multiple hormone interactions in the developmental biology of the mammary gland. Physiol Rev 60:1049-106. 
[2]. Hennighausen, L., Robinson, G.W. (2001) Signaling pathways in mammary gland development. Dev Cell 1:467-475.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

Related Products (1)
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Epithelial Cell Growth Medium MD-0041