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Human Ovarian Microvascular Endothelial Cells (HOMEC)

Human Ovarian Microvascular Endothelial Cells (HOMEC)

Catalog Number: 10HU-070
Availability: Out Of Stock
Price: $549.00

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Product Description

Angiogenesis is critical for many physiological processes including organ development and tissue repair [1]. In human ovaries, angiogenesis is known to be associated with the development of follicles and the formation of the corpus luteum. A complex vascular network is formed within the thecal cell layer during follicular growth, and rapid neovascularization occurs toward the granulosa cell layer after ovulation [2]. Endothelial cells from different organs, as well as from large and small vessels of the same organ, have specialized properties [3]. The endothelial cells prepared from the specific microvasculature of the ovarian follicle are an ideal in vitro model for the study of the angiogenesis and physiology of the female reproductive system.

iXCells Biotechnologies provides high quality Human Ovarian Microvascular Endothelial Cells (HOMEC), which are isolated from human ovary and cryopreserved at P1, with >0.5 million cells in each vial. HOMEC express vWF/Factor VIII, CD31 (PECAM), and Dil-Ac-LDL by uptake. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies. 

Product Details

  Tissue

  Human adipose tissue

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Endothelial Cell Growth Medium (Cat# MD-0010)

References

[1]. Scott, P.A.E. and Bicknell, R. (1993) The isolation and culture of microvascular endothelium. J. Cell Sci., 105, 269-273. 
[2]. Naoko Otani, Sawako Minami, Mareo Yamoto, Toshihiko Shikone, Hisako Otani, Rika Nishiyama, Tsutomu Otani and Ryosuke Nakano (1999) The Vascular Endothelial Growth Factor/fms-Like Tyrosine Kinase System in Human Ovary during the Menstrual Cycle and Early Pregnancy. J. Clinical Endocrinology & Metabolism 84(10)3845-3851. 
[3]. Gerritsen, M. E. (1987) Function heterogeneity of vascular endothelial cells. Biochem. Pharmacol. 36:2701-2711.

[1]. Scott, P.A.E. and Bicknell, R. (1993) The isolation and culture of microvascular endothelium. J. Cell Sci., 105, 269-273. 
[2]. Naoko Otani, Sawako Minami, Mareo Yamoto, Toshihiko Shikone, Hisako Otani, Rika Nishiyama, Tsutomu Otani and Ryosuke Nakano (1999) The Vascular Endothelial Growth Factor/fms-Like Tyrosine Kinase System in Human Ovary during the Menstrual Cycle and Early Pregnancy. J. Clinical Endocrinology & Metabolism 84(10)3845-3851. 
[3]. Gerritsen, M. E. (1987) Function heterogeneity of vascular endothelial cells. Biochem. Pharmacol. 36:2701-2711.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Endothelial Cell Growth Medium MD-0010