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Human Ovarian Surface Epithelial Cells (HOSEpC)

Human Ovarian Surface Epithelial Cells (HOSEpC)

Catalog Number: 10HU-107
Availability: Out Of Stock
Price: $639.00

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Product Description

The ovary is covered by a single layer of surface epithelial cells (HOSEpC) where in vivo morphology varies from squamous to cuboidal to low columnar. HOSEpC actively participate in cyclical ovulatory follicular rupture and the subsequent repair [1]. HOSEpC express a variety of peptide hormones, sex steroids, growth factors, and receptors. Many of these biological agents have been implicated in the development of epithelial ovarian carcinomas [2] and sexually transmitted infections [3]. Understanding aberrations in the corresponding cellular pathways is of great clinical importance as they provide useful information regarding HOSEpC cell survival, apoptosis, transformation, and function during disease development and potential markers for disease treatment.

HOSEpC from iXCells Biotechnologies are isolated from human ovary. HOSEpC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HOSEpC are characterized by immunofluorescence with antibodies specific to cytokeratine-14, -18, and -19. HOSEpC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HOSEpC are guaranteed to further expand for 5 population doublings in Epithelial Cell Growth Medium (Cat# MD-0041).

Product Details

  Tissue

  Human ovary

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Epithelial Cell Growth Medium (Cat# MD-0041)

References

[1]. Murdoch WJ. (1995) Endothelial cell death in preovulatory ovine follicles: possible implication in the biomechanics of rupture. J Reprod Fertil 1995; 105:161-164. 
[2]. Katabuchi H, Okamura H. (2003) Cell biology of human ovarian surface epithelial cells and ovarian carcinogenesis. Medical Electron Microscopy 36(2):74-86.

[1]. Murdoch WJ. (1995) Endothelial cell death in preovulatory ovine follicles: possible implication in the biomechanics of rupture. J Reprod Fertil 1995; 105:161-164. 
[2]. Katabuchi H, Okamura H. (2003) Cell biology of human ovarian surface epithelial cells and ovarian carcinogenesis. Medical Electron Microscopy 36(2):74-86.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Epithelial Cell Growth Medium MD-0041