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Human Peripheral Blood CD4+ Helper T Cells

Human Peripheral Blood CD4+ Helper T Cells

Catalog Number: 10HU-023
Availability: In Stock
Price: $319.00

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Product Description

The CD4+ T cells, also known as T helper cells (Th cells), are a type of T cells that play an important role in the immune system, particularly in the adaptive immune system [1]. CD4+ T cells can regulate immune response through different cytokines secreted [2]. They are essential in B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages.

Considering the diverse and important role CD4+ T cells play in the immune system, it is not surprising that these cells often influence the immune response against disease. CD4+ T cells have been involved in hypersensitivity and as the main target cells of HIV pathogenesis.

iXCells Biotechnologies offers CD4+ T Cells isolated from normal human peripheral blood mononuclear cells (PBMCs) using positive immunomagnetic selection.  > 93% of the cells are CD4+ as showed by flow cytometric analysis (Figure 1).

 

CD4+ T Cells

Figure 1. The purity of CD4+ T cells are >93%. 

Product Details

  Tissue

  Normal human peripheral blood

  Package Size

  1.0x107 cells/vial  

  Passage Number

  P0

  Shipped

  Cryopreserved

  Purity

  >93%

  Growth Properties

  Suspension

  Media

  Blood Cell Culture Medium (Cat# MDBCC)

References

[1]  Hu, J.; Paul, W. E. (2008). "CD4 T cells: Fates, functions, and faults". Blood 112 (5): 1557.

[2]  Toscano MA, Bianco GA, Ilarregui JM, Croci DO, Correale J, Hernandez JD, Zwirner NW, Poirier F, Riley EM, Baum LG, Rabinovich GA. (2007). "Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death". Nat Immunol (8): 825–34.

 Download Datasheet

[1]  Hu, J.; Paul, W. E. (2008). "CD4 T cells: Fates, functions, and faults". Blood 112 (5): 1557.

[2]  Toscano MA, Bianco GA, Ilarregui JM, Croci DO, Correale J, Hernandez JD, Zwirner NW, Poirier F, Riley EM, Baum LG, Rabinovich GA. (2007). "Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death". Nat Immunol (8): 825–34.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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