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Human Prostate Microvascular Endothelial Cells (HPMEC)

Human Prostate Microvascular Endothelial Cells (HPMEC)

Catalog Number: 10HU-073
Availability: Out Of Stock
Price: $549.00

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Product Description

Microvascular endothelial cells play a central role in inflammation, tumor metastasis, wound healing and tissue engineering [1]. They line the blood vessels and contribute to many biological processes such as hematosis, coagulation and trafficking of lymphocytes. The endothelial cell is of primary importance in the extravasation of leukocytes from the circulation into sites of tissue inflammation. The structure and function of endothelial cells are differentially regulated in space and time. In the case of prostate cancer, the interactions between prostate cancer cells with endothelial cells in the microvessels play an important role in prostate tumor metastasis. Study results suggest that prostatic endothelial cells may be actively involved in prostate growth, due to the secretion of regulatory factors such as IL-6 [2] 

iXCells Biotechnologies provides high quality Human Prostate Microvascular Endothelial Cells (HPMEC), which are isolated from human prostate tissue and cryopreserved at P2, with >0.5 million cells in each vial. HPMEC express vWF/Factor VIII, CD31 (PECAM), and Dil-Ac-LDL by uptake. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies.

Product Details

  Tissue

  Human prostate tissue

  Package Size

  0.5 million cells/vial  

  Passage Number

  P2

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Endothelial Cell Growth Medium (Cat# MD-0010)

References

[1] Richard, L., Velasco, P. and Detmar, M. (1998) Isolation and culture of microvascular endothelial cells. Method in Molecular Medicine 18:261-269. 
[2] Stachon, A., Schl?ter, T., K?ller, M., Weisser, H. and Krieg, M. (2001) Primary culture of microvascular endothelila cells from human bening prostatic hyperplasia. Prostate 48(3):156-164.

[1] Richard, L., Velasco, P. and Detmar, M. (1998) Isolation and culture of microvascular endothelial cells. Method in Molecular Medicine 18:261-269. 
[2] Stachon, A., Schl?ter, T., K?ller, M., Weisser, H. and Krieg, M. (2001) Primary culture of microvascular endothelila cells from human bening prostatic hyperplasia. Prostate 48(3):156-164.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Endothelial Cell Growth Medium MD-0010