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Human Pulmonary Artery Endothelial Cells (HPAEC)

Human Pulmonary Artery Endothelial Cells (HPAEC)

Catalog Number: 10HU-029
Availability: In Stock
Price: $599.00

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Product Description

The pulmonary vasculature is of great physiological/pathological significance. Human Pulmonary Artery Endothelial Cells (HPAEC) are critical to maintain the function of the pulmonary circulation and effective diffusion capacity of the lung. HPAEC provide a useful tool for studying various aspects of pathology and biology of the lung vasculature in vitro [1].

iXCells Biotechnologies provides high quality HPAEC, which are isolated from human pulmonary artery from single donors and cryopreserved at P2, with >0.5 million cells in each vial. HPAEC express vWF/Factor VIII and CD31 (Figure 1) and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand for 12 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies.

HPAECs

Figure 1.  HPAEC provided by iXCells are positive for CD31 (A) and vWF (B), as shown by immunostaining.  Flow analysis showed that more than 99% of cells are CD31 positive (A') and more than 97% are vWF positive (B')

Product Details

  Tissue

  Human pulmonary artery 

  Package Size

  0.5 million cells/vial  

  Passage Number

  P2

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Endothelial Cell Medium Kit (Cat# MD-0010) 

References

[1]  Meuchel LW, Thompson MA, Cassivi SD, Pabelick CM and Prakash YS. Neurotrophins induce nitric oxide generation in human pulmonary artery endothelial cells. Cardiovasc Res. 2011; 91(4): 668-676. 

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[1]  Meuchel LW, Thompson MA, Cassivi SD, Pabelick CM and Prakash YS. Neurotrophins induce nitric oxide generation in human pulmonary artery endothelial cells. Cardiovasc Res. 2011; 91(4): 668-676. 

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Endothelial Cell Growth Medium MD-0010