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Human Seminal Vesicle Microvascular Endothelial Cells (HSVMEC)

Human Seminal Vesicle Microvascular Endothelial Cells (HSVMEC)

Catalog Number: 10HU-081
Availability: Out Of Stock
Price: $669.00

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Product Description

The seminal vesicles (SV) are a pair of tubular glands located near the prostate and are essential to the urinary system. They function under androgen control to produce and secrete fluid into the ejaculatory duct. The SV consists of three layers: the inner basal mucosal layer composed of simple cuboidal and pseudo-stratified columnar epithelial cells, the middle muscular layer formed by smooth muscle cells, and the outer layer made up of dense connective tissue. Various pathological conditions can arise in the SV, including congenital SV cysts, seminal vesculitis, and primary and secondary neoplasms [1-3]. Additionally, SV invasion is often used as a prognostic marker in prostate cancer [4]. SV endothelial cells offer unique opportunities to study many features of the SV.

HSVMEC from iXCells Biotechnologies are isolated from the human seminal vesicle. HSVMEC are cryopreserved after purification and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HSVMEC are characterized by immunofluorescence with antibodies specific to vWF VIII and CD31 (PECAM-1) and by uptake of DiI-Ac-LDL. HSVMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HSVMEC are guaranteed to further expand for 10 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010).

Product Details

  Tissue

  Human seminal vesicle

  Package Size

  0.5 million cells/vial  

  Passage Number

  P2

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Endothelial Cell Growth Medium (Cat# MD-0010)

References

[1] Arora SS, Breiman RS, Webb EM, Westphalen AC, Yeh BM, Coakley FV. (2007) CT and MRI of congenital anomalies of the seminal vesicles. AJR Am J Roentgenol. 189: 130-5.
[2] Campobasso D, Fornia S, Ferretti S, Maestroni U, Cortellini P. (2012) Primary bilateral seminal vesicle carcinoma: description of a case and literature review. Int J Surg Pathol. 20: 633-5.
[3] Wang J, Yue X, Zhao R, Cheng B, Wazir R, Wang K. (2013) Primary squamous cell carcinoma of seminal vesicle: an extremely rare case report with literature review. Int Urol Nephrol. 45: 135-8.
[4] Kristiansen A, Wiklund F, Wiklund P, Egevad L. (2013) Prognostic significance of patterns of seminal vesicle invasion in prostate cancer. Histopathology. 62: 1049-56.

[1] Arora SS, Breiman RS, Webb EM, Westphalen AC, Yeh BM, Coakley FV. (2007) CT and MRI of congenital anomalies of the seminal vesicles. AJR Am J Roentgenol. 189: 130-5.
[2] Campobasso D, Fornia S, Ferretti S, Maestroni U, Cortellini P. (2012) Primary bilateral seminal vesicle carcinoma: description of a case and literature review. Int J Surg Pathol. 20: 633-5.
[3] Wang J, Yue X, Zhao R, Cheng B, Wazir R, Wang K. (2013) Primary squamous cell carcinoma of seminal vesicle: an extremely rare case report with literature review. Int Urol Nephrol. 45: 135-8.
[4] Kristiansen A, Wiklund F, Wiklund P, Egevad L. (2013) Prognostic significance of patterns of seminal vesicle invasion in prostate cancer. Histopathology. 62: 1049-56.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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