Human Peripheral Blood CD19+ B Cells Total RNA-3ug
B cells, also known as B lymphocytes, are a subtype of lymphocyte in white blood cells . They play a critical role in the humoral immunity component of the adaptive immune system by secreting antibodies. They also function in immune system as antigen presentation cells and by secretion of cytokines.
CD19 (Cluster of Differentiation 19) is an important surface marker for B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21  and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.
iXCells Biotechnologies offers total RNA isolated from Human CD19+ B Cells (>90% purity). Donors were consenting, healthy adults aged between 20 and 50 years. Donors were negtive for HIVs, HLTVs, HAV, HBV, HCV and syphilis.