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Human Platelets

Human Platelets

Catalog Number: 10HU-230
Availability: In Stock
Price: $99.00
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Product Description

Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.[1] Platelets have no cell nucleus: they are fragments of cytoplasm that are derived from the megakaryocytes[2] of the bone marrow, and then enter the circulation. Circulating unactivated platelets are biconvex discoid (lens-shaped) structures,[3][4] 2–3 µm in greatest diameter.[5] Platelets are found only in mammals, whereas in other animals (e.g. birds, amphibians) thrombocytes circulate as intact mononuclear cells.[4] Platelets play an important role in hemostasis by leading the blood clotting process. 

iXCells Biotechnologies offers human platelets collected in FDA-registered collection centers from healthy IRB consented donors. These human platelets are processed from single donor units of whole blood through apheresis (ACD-A). Human platelets provided by iXCells are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. 

Product Details

  Tissue

  Normal human platelets

  Package Size

  5.0x109 cells/vial

  Passage Number

  P0

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Suspension

  Media

  Blood Cell Culture Medium (Cat# MD-0007)

 

References

[1] Laki K (December 1972). "Our ancient heritage in blood clotting and some of its consequences". Annals of the New York Academy of Sciences. 202 (1): 297–307.
[2] Machlus KR, Thon JN, Italiano JE (April 2014). "Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation". British Journal of Haematology. 165 (2): 227–36.
[3] Jain NC (June 1975). "A scanning electron microscopic study of platelets of certain animal species". Thrombosis et Diathesis Haemorrhagica. 33 (3): 501–7.
[4] Michelson, Alan D. (2013). Platelets (3rd ed.). Academic.
[5] Paulus JM (September 1975). "Platelet size in man". Blood. 46 (3): 321–36. 

[1] Laki K (December 1972). "Our ancient heritage in blood clotting and some of its consequences". Annals of the New York Academy of Sciences. 202 (1): 297–307.
[2] Machlus KR, Thon JN, Italiano JE (April 2014). "Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation". British Journal of Haematology. 165 (2): 227–36.
[3] Jain NC (June 1975). "A scanning electron microscopic study of platelets of certain animal species". Thrombosis et Diathesis Haemorrhagica. 33 (3): 501–7.
[4] Michelson, Alan D. (2013). Platelets (3rd ed.). Academic.
[5] Paulus JM (September 1975). "Platelet size in man". Blood. 46 (3): 321–36. 

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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Blood Cell Culture Medium MD-0007