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Human Brain Vascular Smooth Muscle Cells (HBVSMC)

Human Brain Vascular Smooth Muscle Cells (HBVSMC)

Catalog Number: 10HU-191
Availability: Out Of Stock
Price: $589.00

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Product Description

Vascular smooth muscle cells (VSMC) significantly contribute to the development of vascular disease. The ability of VSMC to switch to a proliferative phenotype in response to environmental stimuli is a major factor in the progression of vascular disease [1]. VSMC express the cell adhesion molecules ICAM-1 and VCAM-1 and studies have suggested that these molecules may promote VSMC proliferation, VSMC differentiation, and vascular inflammation [2]. Human VSMC cultures play a critical role in the continuous advancement of therapies for vascular disease.

iXCells Biotechnologies provides high quality Human Brain Vascular Smooth Muscle Cells (HBVSMC), which are isolated from human brian and cryopreserved at P1, with >0.5 million cells in each vial. HBVSMC express α-smooth muscle actin and desmin and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fung. HBVSMC can further expand for 13 population doublings in Smooth Muscle Cell Growth Medium (Cat # MD-0034) under the condition suggested by iXCells Biotechnologies. 

Product Details

  Tissue

  Human brain

  Package Size

  0.5 million cells/vial  

  Passage Number

  P1

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Smooth Muscle Cell Growth Medium (Cat # MD-0034)

References

[1] Schwartz, S. M., Campbell, G. R., Campbell, J. H. (1986) Replication of smooth muscle cells in vascular disease. Circ. Res. 58:427-444. 
[2] Braun, M., Pietsch, P., Schror, K., Baumann, G., Felix, S. B. (1999) Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc. Res. 41:395-401.

[1] Schwartz, S. M., Campbell, G. R., Campbell, J. H. (1986) Replication of smooth muscle cells in vascular disease. Circ. Res. 58:427-444. 
[2] Braun, M., Pietsch, P., Schror, K., Baumann, G., Felix, S. B. (1999) Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc. Res. 41:395-401.

This product is intended for laboratory research purposes only. It is not intended for use in humans. While iXCells Biotechnologies uses reasonable efforts to include accurate and up-to-date information on this product sheet, we makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. iXCells Biotechnologies does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. iXCells Biotechnologies is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, iXCells Biotechnologies is not liable for damages arising from the misidentification or misrepresentation of cultures.

© iXCells Biotechnologies 2015. All rights reserved.

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