Human Aortic Endothelial Cells (HAOEC)

Description Product Code Price Quantity Add to Cart
Cryopreserved, 0.5 million cells/vial
10HU-020
$689.00

Product Description

Human Aortic Endothelial Cells (HAOEC) line the vessel wall of aorta, the largest artery in the human body. Because HAOECs are constantly exposed to high hemodynamic forces, they produce endothelium-derived substances regulating vasoconstriction and vessel growth [1]. HAOEC also modulate the expression of cellular adhesion molecules to control and fine-tune inflammatory responses and fibrinolysis [2]. These physiological properties allow HAOEC cultures to be widely used in the study of mechanisms for endothelium dysfunction, pathogenesis of vascular diseases and atherosclerosis, and the development of novel disease treatments.

iXCells Biotechnologies provides high quality HAOEC, which are isolated from human aorta and cryopreserved at P2, with >0.5 million cells in each vial. These HAOEC express vWF/Factor VIII and CD31 (Figure 1). They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand in Endothelial Cell Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies. 

Human Aorta Endothelial Cells

Figure 1.  iXCells HAOECs are positive for vVF and CD31. 

Product Details

  Tissue

  Human aorta 

  Package Size

  1.0x106 cells/vial  

  Passage Number

  P2

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Endothelial Cell Medium Kit (Cat# MD-0010)

References

  1. Ando J, and Kamiya A. Flow-dependent regulation of gene expression in vascular endothelial cells. Heart J. 1996; 37:19-32.
  2. Kim M, and Lee YJ. The effect of oxidized low-density lipoprotein (ox-LDL) on radiation-induced endothelial-to-mesenchymal transition. Int J Radiat Biol. 2013; 89(5):356-363.

 Download Datasheet

  1. Ando J, and Kamiya A. Flow-dependent regulation of gene expression in vascular endothelial cells. Heart J. 1996; 37:19-32.
  2. Kim M, and Lee YJ. The effect of oxidized low-density lipoprotein (ox-LDL) on radiation-induced endothelial-to-mesenchymal transition. Int J Radiat Biol. 2013; 89(5):356-363.
Biological
Cell System Cardiac Cell System
Cell System Vascular Cell System
Cell Type Endothelial Cells
Species Human (Normal)