Human Dermal Fibroblasts-adult (HDF-a)

Description Product Code Price Quantity Add to Cart
Cryopreserved, 0.5 million cells/vial
10HU-014-0.5M
$269.00
Cryopreserved, 1.0 million cells/vial
10HU-014-1M
$349.00

Product Description

Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing [1]. The fibroblast is a malleable cell, capable of altering its function and physiology or even transforming into a new cell type, based on its location within the body. The dermal fibroblast also has the unique title of being the first human somatic cell to be induced into a pluripotent stem cell line [2,3].Dermal Fibroblasts (HDF) are the most prevalent cell in human dermis, and one of the most important architects of cutaneous would healing [1]. The fibroblast is a malleable cell, capable of altering its function and physiology or even transforming into a new cell type, based on its location within the body. The dermal fibroblast also has the unique title of being the first human somatic cell to be induced into a pluripotent stem cell line [2,3].

iXCells Biotechnologies provides high quality Human Dermal Fibroblasts (HDF) from either neonatal foreskin (Cat# 10HU-013) or adult skin (Cat# 10HU-014). These cells are derived from the dermis of normal human neonatal foreskin or adult skin and cryopreserved at the end of primary culture. HDF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand in Fibroblast Growth Medium (Cat# MD-0011) under the condition suggested by iXCells Biotechnologies. A Certificate of Analysis is provided for each cell lot purchased.

Applications:

    • iPSC generation
    • ECM protein analysis
    • Wound healing
    • Collagen metabolism
    • Skin therapy/models

 

Human Dermal Fibroblasts

Figure 1. (A) Human Neonatal Dermal Fibroblasts (10HU-013).  (B) Human Adult Dermal Fibroblasts (10HU-014). 

Product Details

  Tissue

  Human Dermal Fibroblasts, Normal (Neonatal foreskin, adult skin) 

  Package Size

  0.5x106 cells/vial,  1.0x106 cells/vial  

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Fibroblast Growth Medium (Cat# MD-0011)

 

 

 Download Datasheet

 

[1] Lauren E. Tracy, Raquel A. Minasian, and E.J. Caterson. (2016) Regulation of Gene Expression by Tobacco Product Preparations in Cultured Human Dermal Fibroblasts. Adv Wound Care (New Rochelle). 5(3): 119–136.

[2] Takahashi K, Yamanaka S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell; 126:663–676.

[3] Kazutoshi Takahashi 1, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell; 131:861–872.

Biological
Cell System Dermal Cell System
Cell Type Fibroblasts
Species Human (Normal)