Human Peripheral Blood CD3+ T Cells (Pan T Cells)

Description Product Code Price Quantity Add to Cart
Cryopreserved, 20 million cells/vial
10HU-009-20M
$699.00
Cryopreserved, 40 million cells/vial
10HU-009-40M
$1,119.00

Product Description

CD3 is a multimeric protein complex, which is composed of four distinct chains (CD3g, CD3d and two CD3e). CD3 complex serves as a T-cell co-receptor that associates non-covalently with the T cell receptor (TCR) [1]. CD3 is expressed in almost all T cell lineages, which make it useful marker for T cells.

T cells exhibit multiple functions including cell-mediated cytotoxicity, promotion of antibody production by B cells, and immune regulation. CD3+ Pan T cells can be divided into several subsets. CD4+ helper T cell, CD8+ cytotoxic T cell and NK cells are the three major subsets. T cells have been widely used in research fields including immunology, infectious diseases, cancer therapy [2] etc.

iXCells Biotechnologies offers CD3+ Pan T Cells isolated from human peripheral blood mononuclear cells (PBMCs) using negative immunomagnetic selection.  These cells are untouched by the separation process and ready for downstream usage. > 86% of the cells are CD3+ as showed by flow cytometric analysis.  

Figure 1. Flow cytometric analysis showed that >86% of the cells are CD3+. 

Product Details

  Tissue

 Normal human peripheral blood

  Package Size

 2.0x107 cells/vial, 4.0x107 cells/vial

  Purity   >86%

  Passage Number

  P0

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Suspension

  Media

  Blood Cell Culture Medium (Cat# MD-0007)

 

Reference

[1]  Smith-Garvin JE, Koretzky GA and Jordan MS. T cell activation. Annual Review of Immunology 2009:27: 591-619.

[2]  Vigneron N. Human Tumor Antigens and Cancer Immunotherapy. Biomed Res Int. 2015.

 Download Datasheet

[1] Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M. Manual of Diagnostic Cytology (2 ed.). Greenwich Medical Media, Ltd. pp. 63–64 (2003). 

Biological
Cell System Hematopoietic Cell System
Cell Type Immune Cells AND Hematopoietic Cells
Species Human (Normal)