Human Peripheral Blood CD34+ Cells

Product Description

CD34, a transmembrane glycoprotein expressed on the surface of hematopoietic progenitor cells and small blood vessel endothelial cells, is regarded as a marker of hematopoietic stem cells (HSC) and hematopoietic progenitor cells ^[1]. CD34+ cells have been shown to possess colony-forming potential in short-term assays, maintain long-term colony-forming potential in in vitro cultures and allow the expression and differentiation of blood cells from different hematopoietic lineages in in vivo models ^[2]. The CD34+ Progenitor Cells contain two main cellular subpopulations, hematopoietic and endothelial progenitor cells. Therefore, CD34+ Progenitor Cells are suitable for a series of studies, e.g. directed differentiation into more committed types of blood cells and endothelial lineages.

iXCells Biotechnologies offers CD34+ Progenitor Cells from the peripheral blood of healthy donors. These cells are positively isolated using a direct immunomagnetic CD34 MicroBead labeling system.  > 90% of the cells are CD34+ as showed by flow cytometric analysis of iXCells CD34+ Progenitor Cells.

Figure 1: The representative flow cytometry analysis result of Human Peripheral Blood CD34+ Cells.

Product Details

References

[1] Julie S. Nielsen, Kelly M. McNagny (2008). “Novel functions of the CD34 family.” Journal of Cell Science 121, 3683-3692.

[2] M Engelhardt, M Lu¨bbert and Y Guo. (2002). “CD34+ or CD34− : which is the more primitive?.” Leukemia, 16:1603-1608.

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