Human Platelets

Description Product Code Price Quantity Add to Cart
Cryopreserved, 500 million cells/vial
10HU-230
$107.00

Product Description

Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.[1] Platelets have no cell nucleus: they are fragments of cytoplasm that are derived from the megakaryocytes[2] of the bone marrow, and then enter the circulation. Circulating unactivated platelets are biconvex discoid (lens-shaped) structures,[3][4] 2–3 µm in greatest diameter.[5] Platelets are found only in mammals, whereas in other animals (e.g. birds, amphibians) thrombocytes circulate as intact mononuclear cells.[4] Platelets play an important role in hemostasis by leading the blood clotting process. 

iXCells Biotechnologies offers human platelets collected in FDA-registered collection centers from healthy IRB consented donors. These human platelets are processed from single donor units of whole blood through apheresis (ACD-A). Human platelets provided by iXCells are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. 

Product Details

  Tissue

  Normal human platelets

  Package Size

  5.0x109 cells/vial

  Passage Number

  P0

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Suspension

  Media

  Blood Cell Culture Medium (Cat# MD-0007)

 

References

[1] Laki K (December 1972). "Our ancient heritage in blood clotting and some of its consequences". Annals of the New York Academy of Sciences. 202 (1): 297–307.

[2] Machlus KR, Thon JN, Italiano JE (April 2014). "Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation". British Journal of Haematology. 165 (2): 227–36.

[3] Jain NC (June 1975). "A scanning electron microscopic study of platelets of certain animal species". Thrombosis et Diathesis Haemorrhagica. 33 (3): 501–7.

[4] Michelson, Alan D. (2013). Platelets (3rd ed.). Academic.

[5] Paulus JM (September 1975). "Platelet size in man". Blood. 46 (3): 321–36. 

[1] Laki K (December 1972). "Our ancient heritage in blood clotting and some of its consequences". Annals of the New York Academy of Sciences. 202 (1): 297–307.
[2] Machlus KR, Thon JN, Italiano JE (April 2014). "Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation". British Journal of Haematology. 165 (2): 227–36.
[3] Jain NC (June 1975). "A scanning electron microscopic study of platelets of certain animal species". Thrombosis et Diathesis Haemorrhagica. 33 (3): 501–7.
[4] Michelson, Alan D. (2013). Platelets (3rd ed.). Academic.
[5] Paulus JM (September 1975). "Platelet size in man". Blood. 46 (3): 321–36.