Rat Cortical Neurons (RCN)

Description Product Code Price Quantity Add to Cart
Cryopreserved, 2.0 million cells/vial
10RA-032
$499.00

Product Description

Cortical neurons make up a large portion of the brain and consist of both glutamateric and GABA-ergic neurons [1].  They play an important role in higher level thought processes and are necessary to organize input from subcortical structures.   Like all neurons, these cells transport Na+ that work to propagate action potentials from one cell to the next, which is the basis of a working neural pathway.  These cells can be used to study a variety of cortical related abnormalities including Huntington’s Disease, Alzheimer’s Disease, psychiatric disorders, and learning disorders [2, 3].

iXCells Biotechnologies provides high quality Rat Cortical Neurons (RCN), which are isolated from the brains of E16 embryonic rats.  These cells are cryopreserved at P0, with ≥ 2 million cells in each vial.  They are negative for mycoplasma, bacteria, yeast, and fungi. RCNs can be plated using Rat Cortical Neuron Recovery Medium (Cat# MD-0107A) and maintained in Rat Cortical Neuron Maintenance Medium (Cat # MD-0107B) under the condition suggested by iXCells Biotechnologies.

Rat Cortical Neurons

Figure 1. Rat Cortical Neuron (Cat# 10RA-032) were recovered and cultured for 5 days. (A) Phase contrast image. (B) Immunofluorescence staining were performed using antibodies against the neuronal markers MAP2 (green) and NeuN (red). 

Product Details

  Tissue

  D16 embryo rat brain tissue

  Package Size

  2.0 million cells/vial  

  Passage Number

  P0

  Shipped

  Cryopreserved

  Storage

  Liquid nitrogen

  Growth Properties

  Adherent

  Media

  Rat Cortical Neuron Recovery Medium (Cat # MD-0107A)

  Rat Cortical Neuron Maintenance Medium (Cat# MD-0107B)

 

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Reference

[1] Johnson M, Walsh C. (2017) " Cerebral Cortical Neuron Diversity and Development at Single-Cell Resolution " Curr Opin Neurobiol. 42: 9-16.

[2] Lim L, Mi D, Llorca A, Marin O. (2018) " Development and functional diversification of cortical interneurons." Neuron. 100(2): 294-313.

[3] Molnár Z, Clowry G J, Šestan N, Alzu’bi A, Bakken T, Hevner R F, et al. (2019) " New insights into the development of the human cerebral cortex." J. Anat. 235: 432-451.

 

* Holiday discount is not applicable to this product *

[1] Johnson M, Walsh C. (2017) " Cerebral Cortical Neuron Diversity and Development at Single-Cell Resolution " Curr Opin Neurobiol. 42: 9-16.

[2] Lim L, Mi D, Llorca A, Marin O. (2018) " Development and functional diversification of cortical interneurons." Neuron. 100(2): 294-313.

[3] Molnár Z, Clowry G J, Šestan N, Alzu’bi A, Bakken T, Hevner R F, et al. (2019) " New insights into the development of the human cerebral cortex." J. Anat. 235: 432-451.

Biological
Cell Type Fibroblasts
Species Rat