DCIP-1/CXCL3, Mouse
| Description | Product Code | Price | Quantity | Add to Cart |
|---|---|---|---|---|
|
10ug
|
IX02905-10
|
$159.00
|
||
|
1mg
|
IX02905-1
|
$2,100.00
|
Overview
| Synonyms | DCIP-1 Murine; CXCL3 Murine |
| Description | Dendritic cell inflammatory protein-1 (DCIP-1)/CXCL3 is also known as MIP2β (macrophage inflammatory protein 2 beta), or DCIP1 (dendritic cell inflammatory protein-1) in mouse, CINC2 (cytokineinduced neutrophil attractant 2) in rat, and GROγ (growth regulated oncogene gamma) in humans. It is an 8 kDa proinflammatory member of the CXC subfamily of heparinbinding chemokines, also called alpha chemokines. Mature mouse CXCL3 shares 88% and 57% amino acid (aa) sequence identity with rat and human CXCL3, respectively. |
| Species | Mouse |
| Source | E. coli |
| Biological Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/ml. |
| Sequence | AVVASELRCQ CLNTLPRVDF ETIQSLTVTP PGPHCTQTEV IATLKDGQEV CLNPQGPRLQ IIIKKILKSG KSS |
Properties
| Measured Molecular Weight | Approximately 7.9 kDa, a single, non-glycosylated polypeptide chain containing 73 amino acids. |
| Purity | > 97 % by SDS-PAGE and HPLC analyses. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Endotoxin Level | Less than 1 EU/μg of rMuDCIP-1/CXCL3 as determined by LAL method. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Storage | This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles. |
| Note | ; |
| Biological | |
|---|---|
| Source | E. coli |
| Species | Mouse |